Cardio3 BioSciences teams up with Medisun International to create Cardio3 BioSciences Asia Holdings Ltd, a Joint Venture aimed at conducting pivotal clinical programs in Greater China
• The minimum of 20M€ funding of the Joint Venture over the next three years is secured by local financial investors led by Hong Kong based Medisun International Ltd.
• The clinical program aims to lead to the commercialization of C-Cure® in the People’s Republic of China, Hong Kong and Taiwan.
• Medisun will also bring local regulatory, clinical and market access knowledge, while Cardio3 BioSciences will bring clinical and operational knowhow and expertise.
• With this additional clinical program in Asia, Cardio3 BioSciences will have access to the third largest pharmaceutical market in the world.
• The quality standards of the Asian operations will be managed by Cardio3 BioSciences, with the same rigor as the European and American operations.
Mont-Saint-Guibert, Belgium, 16 JUNE 2014 – Cardio3 BioSciences SA (C3BS) (Euronext Brussels and Paris : CARD), leader in the discovery and development of advanced regenerative therapies for heart disease, today announces it has entered into an agreement with Medisun International Limited, a financial investor based in Hong Kong aiming to build a life science portfolio, for the purpose of creating a joint venture to conduct Phase III clinical trials in Greater China (the People’s Republic of China, Hong Kong and Taiwan) potentially leading to the commercialization of C-Cure® in these territories. Medisun International Limited is also a shareholder of Cardio3 following a capital increase, the first phase of which became effective today.
The Joint Venture, named Cardio3 BioSciences Asia Holdings Ltd, will be created with the purpose to conduct pivotal clinical trials in Greater China, ie the People’s Republic of China, Hong Kong and Taiwan. Cardio3 BioSciences will bring to the Joint Venture the required IP rights to conduct a clinical trial in those geographies, the use of its C-Cure® manufacturing capabilities based in Mont-Saint-Guibert (Belgium) that will produce the clinical lots for the Phase III program, and its clinical and operational knowhow and expertise. Medisun will bring to the joint venture the funding required for the execution of the clinical trials, with a minimum committed of 20M€ over a three year period, as well as local knowledge of the clinical and regulatory environment.
Cardio 3 BioSciences’s ownership in the Joint Venture will be 40%, to be reduced to 30% when clinical trials are running in the three geographies.
A successful outcome of the Phase III clinical program in those geographies would trigger the right for the joint venture company to commercialize C-Cure® in those territories with royalties ranging between 20 and 30% of net sales depending on total revenue of the Joint Venture.
The obligations under the joint venture agreement are still subject to the completion of the second tranche (for 12.5M€) of a 25 M€ investment in Cardio 3 BioSciences by Medisun on 30 June 2014.
With clinical programs ongoing in Europe and Israel, and soon in the USA and Greater China (People’s Republic of China, Hong Kong and Taiwan), Cardio3 BioSciences confirms its leadership in the cardiac regenerative field with its global presence.
Dr Christian Homsy, CEO of Cardio3 BioSciences, said: “We are delighted to have the opportunity to access the world’s third largest pharmaceutical market at limited costs to Cardio3. In cooperation with a reputable local partner, we look forward to soon initiating one or more pivotal trials that would lead us towards commercialization in the world’s fastest growing economy. We are also delighted that both partners are committed to the most rigorous standards of pharmaceutical practices and scientific integrity.”
Mr Michel Lussier, Chairman of Cardio3 BioSciences, added: “With this presence in Greater China, we are very proud to become the first global player in the field of cardiac regenerative medicines, aiming to commercialize our leading edge cell therapy to patients all across the globe.”
Mr Danny Wong, Chairman of Medisun International Holdings Ltd., added: “I am very proud that we are able to pioneer the clinical development of this exciting technology in China and potentially later on in Asia. Our ultimate goal is to deliver this live-saving treatment to countless patients with heart problems.
We shall organize symposia this August in Beijing and Shanghai to promote cell based medicines as well as Cardio3’s technology. Leading experts from Europe, US and Asia will attend this event which will enable us to reach out and unite biomedical experts in this part of the globe.
We are passionate about this project and I am certain that our involvement with Cardio3 as a leader in this field, combined with our local knowledge of the regulatory, healthcare and market access capabilities and expertise, will bring success to all the parties involved.” See more info on http://www.medisun.hk/.
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Adjustable Extraction Tips and 150 CFM Airflow. With 110V power, the portable fume extractor can generate 150 CFM airflow with its 2.3 HP motor. You can adjust the tips of extraction as per your welding requirements. Efficient Dust Collector and Suitable for Various Welding Tasks. I’ve found the dust collector in this weld fume extractor to be quite effective. You can even buy an additional hood for specialized uses. The S130/G130 generates 75 dB sounds when it runs on full power. You can efficiently use this machine for MIG welding, GMAW, stick welding, and gas metal arc welding.
This drill has a powerful 9 Amp motor, high-end 2-coil magnet, and compatible with ¾” diameter shank annular cutters. To start off, this drill is very proud of how easy it is to handle. It weighs a mere 26.5 pounds and it has a conveniently located handle, making uncomfortable drilling positions more bearable. It has a straightforward 2-button control panel that is also conveniently located and easy to use. Other perks that you get with this drill is a hard case and, depending on where you buy, you may also receive a kit containing German-made annular cutters. Like some of the other drills in this list, you can also fit the feeding handles on either side of the drill, depending on what is ergonomic and comfortable for you. This drill also has an easy to turn off feature to add an element of safety to your drilling. This button is big and easily accessible. This is a solid drill that is perfect for all handymen.
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Our welding tables are to be self-assembled. This is an easy process; full instructions are provided. A wide range of tools are available for use with these tables and they are available as added optional extras in the custom options above. If you require guidance on which tool set would be the most suitable for you please feel free to call our helpful staff. *Please note that current lead times on these welding tables are 3-4 weeks, however if you require the table quicker please alert us and we will do our best to assist with your enquiry*
The Hobart Handler 210 has the typical great quality Hobart build with durable parts that stand the test of time. The 210 is more suited to autobody repair and construction than the 190 and 140 and it welds up to 3/8 inch. It’s also a flexible unit with the capacity to weld off 115V and 230V. At under $1000 it’s lot cheaper than the Ironman 230 and is a wise choice if you’re looking for a welder that packs real power but isn’t the price of the heavy industrial welders. It you’re looking for the all round MIG package for power, versatility, quality and value for money, the Hobart 210 is our top pick. See our full review of the Hobart Handler 210 here.
It’s another gasless MIG welder manufactured by Wolf. The Wolf MIG 130 yields the output range of 50? – 120? that enables welding metalware up to 6mm thick. It is possible thanks to 2 toggles that provide a varying output power for a specific part. In addition, you can set one of 10 wire feed speeds, so that welding could be fully under your control. As for the welder unit, it will let you control all processes and stability of operation thanks to handy indicator lights. Once the tool has been used for too long and requires a break from work, a corresponding light will flash up warning you to make a pause. However, owing to the built-in cooler, the runtime of the welder is still pretty long and should be enough for most jobs. Being small and lightweight like it is, the Wolf 130 welder’s output makes only 13A which won’t be sufficient for tough welding tasks unless you’ve been planning to replace the wiring in your place anyway. The shipping package isn’t wide too and includes only a spool of a 0.8mm wire.
United Kingdom market pick: Many veteran welders would agree that the greatest advantage that comes from a metal inert gas MIG welder is its speed. The pace of these premium and cheap welders is unmatched when compared to stick welding and TIG welding, both of which can take a bit longer. For this reason, the metal inert gas welder allows for much faster production rates than the other welding processes (which is a reason for their being used so often in mass production).
Important Industrial Gas Cylinder Safety Guidelines to Keep in Mind: Acetylene and oxygen are two industrial gases widely used across various industries. The cylinders accommodating these gases are designed with user’s safety in mind. However, that is not enough to ensure optimum safety in an industrial facility. The following factors will help ensure the same: Understand the Cylinder Properly: A personnel should be familiar with the potential risks and hazards associated with compressed gases while handling them. It is important to understand the properties of the gas filled within such as toxicity, flammability limits, and toxicity – Threshold Limit Value (TLV). Also, it is important to understand the hazards posed by gas at low temperature, high pressure or due to the physical state of the gas – non-liquefied or liquefied, etc. A personnel should read the contents of the label on the cylinder. If the label is missing or not easily readable, then the cylinder should not be used. In addition to improving a personnel’s understanding on oxygen cylinder safety or acetylene cylinder safety, he should be administered a proper plant safety training.
The S SATC PCS Metal Cutting Disc for Angle Grinder is made with a proprietary aluminum oxide grain combination that creates an aggressive cutting action. This allows the user to cut through materials more easily. In addition, the wheel also has a balanced Cut Life, Cut Rate, Cut Precision, Power Demands & Heat Buildup. This means that you can cut through materials for longer periods of time without having to worry about the accuracy of the cut or the heat that is being generated. The SATC PCS Metal Cutting Discs will cut through most surfaces with ease and do not slow down as they work like other standard discs. These new discs also last much longer than other brands which allows you to make even more cuts before needing a replacement disc.
Water park manufacturer and supplier in China: A Blow-Up Water Park Is Social And Active: As we all know, social interaction is crucial to a healthy lifestyle. Blow Up Water Parks provide an excellent opportunity for people to bond and interact with each other. Additionally, the physical exercise in navigating the obstacles in our water parks provides a fun and engaging workout. Bouncia believes that a healthy water sport is bound to attract many guests. And guests will be willing to pay for entertainment, including social interaction and physical exercise. Read more information on Bouncia water park.
Cost-effective: Compared to permanent water features, it is more affordable, making it a great option for families on a budget. Additionally, it does not require professional installation or maintenance, further reducing its cost. With its affordability and ease of use, a giant inflatable water slide provides more value for your money, making it a smart investment for families looking to enjoy a fun and refreshing summer without breaking the bank. Whether you’re looking for a summer accessory for your home or just want to add a fun and exciting touch to your outdoor events, a giant inflatable water slide is the perfect choice for anyone looking for a cost-effective way to enjoy their summer.
For production time, normally most inflatable water park manufacturers are busy after Chinese New Year. It’s better to place order before January so that your order can be arranged first. For custom order, most manufacturers production time is within 50 days exclusive of 20 days Chinese new year holiday. How can we do to avoid such problem happen? According to current situation, COVID-19 is still making the shipment much longer than normal years. For sea shipment, you’d better allow 2-3 months extra time for shipping. For example, if normal transit time is 30 days, to be on the safe side, you need to consider the transit time 3-4 months. If you do not have enough time to choose sea shipping, you can consider to ship by air or by train. But you also need to allow longer time than normal times.
To solve this problem, Bouncia inflatable water park manufacturer made innovation based on the traditional air constant inflatable fun city(water bouncy castle). We made it air sealed. The fun cities can be filled 10cm deep water to bring more fun for kids. They can be put on land or float on water. In the summer, you can use it as inflatable water park for kids. In the winter, you can use it as dry inflatable bouncy castle. It’s also designed with drainage hole and other system so that the water can flow out.
Bouncia floating Inflatable water parks or inflatable amusement parks combination is designed based on capacities or water areas of differing sizes. If the standard combination is satisfactory, but you prefer some minor changes such as the color or some single elements, please tell us. We can amend them for you accordingly. These are part of Bouncia inflatable water parks projects in different countries. If you want to experience Bouncia inflatable water playground in person but cannot find a project location near you, please contact us. A Bouncia Inflatables sales representative will check for nearby projects which may not currently appear on this list.
Without the non-slip socks, the inflatable water park is very slippy and caused injuries. The grip socks increased the traction and reduce the slips and trips. Reduce insurance cost for your park: With risks of injuries reduced, your insurance cost will be also less for the next year. This can also make a good reputation for your park, which will attract more and more customers. Enhance customers experience: The grip socks also protect your visitors’ feet against hot sand, stony surfaces and underwater hazards, offering a more enjoyable experience both on and off your floating aqua park.
How much profit can a waterpark make? This industry has realized significant growth over the last decade and is expected to continue at approximately 3.5% annually. While there are is no published information regarding a water park’s potential profit, research does indicate that over 375 million guests visit these establishments in the United States each year. With a meticulous operational strategy in place, your park can earn a piece of this multi-billion dollar industry’s profits.
In the case of inflatable water parks we have served, all in one station is one of the most popular and exciting items. It has been a big hit for several water park locations such as Perth water park in Australia, Kiwi water park in New Zealand, Splash and dash water park in the USA. This is a giant item combined with diving, climbing and sliding. You can either connect it with other water obstacles or use it as a standalone item. All parts are removable and can be easily replaced if necessary. The positions of the two slides and jumps are interchangeable. The oversized, playable and multifunctional all in one station can bring a lot of visitors to your inflatable water park!
Free customized design solutions are one of our advantages. We have been offering custom solutions for clients from multiple countries. These custom parks are both successful and unique. Today we are proud to say that we are the leading expert on customized inflatable water parks. In addition to customized solutions, we also provide standard water park options with a variety of capacities. The advantage of choosing our standard color and design combination is that order processing is faster than customized solutions. Discover extra information on https://www.bouncia.com.cn/.
Video games testing paid work jobs with gametesterx 2023: Game Tester is a platform where developers interact with the community and ask the important questions to find the hard truths that make or break their games. Do you think this game is worth $50? There are thousands of bugs in games that developers overlook and these bugs impact on a gamers enjoyment and likelihood of giving a positive review or referral. Game Tester helps bring the facts to the developers in measurable data that can be acted upon. In return for your feedback, you will be awarded. Duties of a Game Tester: Test video game titles on various consoles, PCs and handhelds to check the software for errors and enter them into the test database. Reports to the Lead and/or QA Manager. Provide a positive role model, in terms of both work performance and attitude. Discover more information at https://twitter.com/Gametesterx.
Gain some firsthand experience. You can do this by participating in public beta tests of games and interning at gaming companies. Beta testing gives you firsthand experience with a developing project, which you can further supplement by writing about your experiences. Interning at a gaming company can help you get your foot in the door and allow you to talk to seasoned programmers. The more experience you can add to your resume, the better. Build a strong resume. Creating a resume that is attractive to developers is critical to land a testing job. This means you should customize your resume for each company you apply to based on the specific job posting. Highlight skills and experience that match the required core skills. Finally, since game developers look for the most detail-oriented candidates, proofread your resume before submitting it to ensure there are no grammatical errors.
Sometimes an unfinished game is released. Does it mean you failed as a tester? Not really. This happens when somebody purposely lets a game pass testing. QA game testers know about all the bugs but, in spite of that, a final decision may be made to not address some of the less important issues. Management, the producer, or the main developer may decide that a game is good enough for release for one reason or another. It’s something that needs to be clearly communicated and agreed upon with other parties, but if you know you did everything you could to improve a game, then at least you can rest easy that you did your part for the players.
PC games testing paid work jobs with Gametesterx.com 2023: How much does each test pay? You get paid $25 for each game you test. Games take 1 – 2 hours to complete and rate. Once you complete 150 test you will become eligible to apply for higher paying test. When do I get paid? You get paid at the end of everyday via Direct Deposit. All earnings from each game you complete will be bundled together for a total of 1 payout per day. (PST – 11:59pm). Payout Methods? You will receive daily payouts to your Bank Account that you link to your Game Tester account. Test Availability? We partner with hundreds of game developers nationwide, so there are thousands of test available everyday. You will have a minimum of two test available each day. After you complete your two test you will be able to select other available tests which are first come first serve.
Record everything and look for patterns: I’ve come up with this rule after some not-so-good reproductions. Recording is useful because you’ll already have both a video of the bugs and all the repro steps for other people to see. After watching the recording, you can reproduce the steps, look for patterns, check alternative scenarios, and congratulations! You found a bug! Okay, maybe it’s not a reason to celebrate, but it’s still better than having the players find it.
There are many other jobs you could pursue if you wish to work in the video game ecosystem, all with different and equally important demands. These include serving as a writer, animator or developer. This article is for avid gamers who want to become professional video game testers for developers and publishers. As the popularity and complexity of video games continue to increase in the United States, there’s a need for dedicated, detail-oriented video game testers to take on a critical role in the video game ecosystem. Video game testers fill the same role as other quality assurance (QA) software developers: They ensure that games meet the requirements and standards the game company and designers defined when envisioning the product. Find more details on Video Games tester.
Top rated 2 axis cnc lathe machine supplier: A view inside the enclosure of a CNC Swiss-style lathe/screw machine: A Swiss-style lathe is a specific design of lathe providing extreme accuracy (sometimes holding tolerances as small as a few tenths of a thousandth of an inch—a few micrometers). A Swiss-style lathe holds the workpiece with both a collet and a guide bushing. The collet sits behind the guide bushing, and the tools sit in front of the guide bushing, holding stationary on the Z axis. To cut lengthwise along the part, the tools will move in and the material itself will move back and forth along the Z axis. This allows all the work to be done on the material near the guide bushing where it is more rigid, making them ideal for working on slender workpieces as the part is held firmly with little chance of deflection or vibration occurring. This style of lathe is commonly used under CNC control. Discover additional info on cnc lathe machine manufacturer.
Numerical control (NC) is the automation of machine tools that are operated by precisely programmed commands encoded on a storage medium, as opposed to controlled manually via hand wheels or levers, or mechanically automated via cams alone. Most NC today is computer numerical control (CNC), in which computers play an integral part of the control. In modern CNC systems, end-to-end component design is highly automated using computer-aided design (CAD) and computer-aided manufacturing (CAM) programs.
CNC machine center is indispensable in diverse industries for manufacturing progress. CNC lathe has been widely using in mechanical manufacturing to solve the complex, precision, small-batch, multi-variety parts processing process. It is a flexible and efficient automatic machine tool, represents the development direction of modern machine tool control technology, is a typical mechanical and electrical products, and occupies a pivotal position. With the rapid development of precision machining technology and the continuous improvement of machining accuracy of parts, higher requirements are put forward for the customized precision of CNC(computer numerical control) lathe. They are high precision cutting tools.
What does a vertical machining center do? A vmc can perform milling, boring, drilling, tapping, thread cutting, and more operations. What are vertical machining centers typically used for? VMCs are typically used for flatwork that requires tool access from the top, for instance for mold and die cavities and large components for planes, especially in the manufacturing industry for the high-precision production of parts. What’s the difference between a horizontal and vmc? Horizontal machining centers have x–y table with cutter mounted on a horizontal arbor across the table. Vertical machining centers have its spindle axis vertically oriented. Its milling cutters are held in the spindle and it rotates on its axis.
Compared with the horizontal machining center, the structure of the vertical machining center is simpler, with a smaller floor space and cheaper price. Due to its advantages and characteristics, CNC VMC machine can be used in aerospace, automobiles, instruments, textiles, electronics and electrical, mould manufacturing, military, handicrafts and other machinery manufacturing industries that require high precision and mass production. VMC vertical machining center is mainly suitable for processing complex shapes, high precision, and multi-process workpieces. Let me introduce to you what parts the vertical machining center can process. See extra details on https://www.jsway-cnc.com/.
Our goal is to become a well-known brand manufacturer of CNC lathe machine in China, specializing in the production of high-precision multi-functional small and medium-sized CNC machine tools, to achieve reliable quality, performance and international standards, product expertise, multi-functional milling and laminating. CNC lathe for sale, contact us! Machining Repositioning accuracy fluctuating less than 0.007mm in Cold & warm state. Key parts all from Taiwan and Japan brand.–make sure the high precision and quality stable.
Top rated advantages to hire a flexible Chief Financial Officer with Sam McQuade CFO: Are a CEO and a CFO the Same Thing? No, a CEO and a CFO are not the same thing. However, CFOs are required to work closely with the other senior executives of a company, such as the CEO. These executives are sometimes referred to as the C-Suite of the company, representing the company’s highest level of decision-making. Although the CFO is typically subordinate to the CEO in the corporate hierarchy, CFOs will generally be the foremost decision-maker on all matters within the Finance department of their firm.
In these early years of creating innovations in the corporate C-Suite, Sam McQuade nurtured and created a maverick approach to new finance operations for Stryker as it broke through to the lucrative emerging markets in Central and Eastern Europe (CEE)). While approaching the markets in the growing economies of Poland, Czech Republic, Hungary, Croatia and Romania, Sam McQuade was recognizing the need for Interim and Fractional CFO’s for the avalanche of incubators and startup companies in these underdeveloped economies that were on the cusp of being integrated into modern International Finance systems and markets. Discover even more information on Sam McQuade CFO.
CFOs usually are responsible for key finance functions which have included broad categories of accounting, treasury, financial planning and analysis (FP&A), controls, compliance, tax, and audit. Going forward towards 2022, the same functions exist, but they are getting more automated, so the CFO can focus more on forward perspectives. Storytelling requires strong emotional intelligence and solid communication skills. Here’s the four key areas the CFO can be messaging: Why & Purpose: Communicating the “Why” is one of the strongest messages the CFO can deliver. It’s not only the reason for the corporate existence, but it’s also very motivational for all the stakeholders. This message should be repeated frequently and consistently to make people feel the genuine purpose.
Strategy and forecasting involves using available data and reports, both internal and external, to advise on areas including product development, market expansion, human capital management, M&A and capital investments. It’s also where structured planning and forecasting exercises, like scenario planning and FP&A, fall. Controllers, treasurers and FP&A analysts are invaluable members of the team, but in all these areas, the buck stops at the CFO’s desk.
The option of working from anywhere in the world is another advantage of a DAO. In a traditional organization, you have to be physically present in order to participate in the organization. With a DAO, you can participate from anywhere in the world. All you need is an internet connection. There are many other examples of DAOs, and there are many different ways in which they can be used. The possibilities are endless, and it is up to the creativity of the developers to come up with new and innovative ways to use them.
What Does a Fractional CFO do for a Company? Fractional CFOs most commonly partner with companies to help overcome financial challenges, achieve growth, optimize strategy, implement systems, raise capital, or navigate an audit or transaction. Overcoming Specific Challenges: Fractional CFOs are often brought into an organization when there are financial challenges that the company’s existing team does not have either the skills or manpower to overcome. In many cases, a company does not have an in-house CFO. In some cases, however, the company may have an existing CFO, and the fractional CFO acts as a partner or advisor or helps lead separate projects such as raising capital or navigating an audit.
Are you looking to expand your business overseas? Our experts are able to help you at any stage. We will first start by understanding your vision and global tax and cash strategy. Once aligned, we will help execute the financial, legal, compliance and talent solution activities to build your entity and team.
A DAO is a decentralized autonomous organization that is run by smart contracts on the Ethereum blockchain. It is an organization or company that is not centrally controlled by any one person or entity. Rather, it is governed by code that is written into the smart contracts. This code can be modified or updated by anyone who has access to the DAO’s GitHub repository. To put this into perspective, imagine a traditional company or organization. There is usually a board of directors or executive team that makes all the decisions about how the company will be run. With a DAO, there is no such thing. The code that governs the DAO is open source and available for anyone to view and audit. In this new scenario, an organization can be run by anyone in the world who has an internet connection.
To summarize, a fractional CFO brings all the benefits of a full-time resource, but at a fraction the cost. They work an agreed upon amount of time, and on an ongoing basis. The benefits are myriad, and range from improved reporting and decision-making, clearer insight into the business for planning and forecasting, and stronger financial management and controls. Perhaps the biggest benefit however, is how the CEO can transfer the financial and administrative burden to the CFO, and thus free themselves to work on other critical aspects of the business.
Searching to hire your first CFO or wanting only some interim coverage? We offer solution CFOs for urgent short term objectives and longer term engagements. Adaptable with fair pricing so you cover your business and don’t have to get into a potentially bad and costly full time hire. Along with the core services of C-Suite Level Executives in Finance and a contingent of Fractional CFO talent and experienced Intermittent CFO innovators, Panterra Finance services include: international Business – Experts in Global Tax Liabilities and Cash Flow Strategies, investments and planning. Mergers and Acquisitions (M&A) Advisory – Providing valuations as well as independent perspectives on offers and options. Internal Audits – Independent internal auditors with in-depth reports highlighting risks and vulnerabilities. Risk Management – A worldwide footprint enables Panterra Finance to identify risks and opportunities in the new world economy. Compliance Review – Actionable understanding when entering markets with new rules, regulations, laws and international asset allocation decisions. Discover extra info on Sam McQuade.